Quick answer: Methylene blue can interact with antidepressants and other serotonin-affecting medicines, and may be unsuitable for people with G6PD deficiency. Check with a physician before use, and take only as directed.
Possible effects
Blue or green urine is commonly mentioned and is generally described as harmless. Upset stomach or headache can occur with many supplements. Stop use if you feel unwell.
Who should avoid it or ask first
- Antidepressants and serotonin-affecting medicines: SSRIs, SNRIs, tricyclics, MAOIs and similar medicines can interact with methylene blue, with a risk of serotonin syndrome. Do not combine without medical advice.
- G6PD deficiency: methylene blue can harm red blood cells in people with this condition.
- Pregnant, nursing or under 18: do not use.
- Other prescription medication: ask your pharmacist or physician first.
- Kidney disease or potassium-affecting medicine: potassium and zinc may matter.
Not a treatment
The featured product is a dietary supplement, not a treatment for memory loss, dementia, depression or any other condition. See the full disclaimer.
When to see a doctor
Agitation, fever, rapid heartbeat, tremor, confusion, dark urine with weakness or yellowing skin, chest pain or shortness of breath need urgent medical attention. New or worsening memory problems should be evaluated by a healthcare professional.